Dihexa is an oligopeptide drug and an angiotensin IV analogue. It is orally bioavailable and capable of crossing the blood‑brain barrier. This compound exhibits high binding affinity for hepatocyte growth factor, and can upregulate the activity of its receptor .Preclinical animal studies have demonstrated that Dihexa exerts prominent antipsychotic properties and improves cognitive performance. Accordingly, it holds promising potential for the research and therapeutic development of Alzheimer’s disease.

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